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The narrative of Medicine revolves around Naoki and his female cousin Yayoi, who are staying at Naoki's house with their families. While the adults mingle downstairs, Naoki pretends to have asthma and lays in his room. In actuality, he is feeling down and has caught a cold after being rejected by a girl he had feelings for. However, Yayoi notices his ploy and barges into his room to ask about his troubles. Though Naoki is initially hesitant, he eventually confides in her. Luckily, Yayoi extends her sympathy and gives him a "good luck charm" to help him feel better...
Shuka, a lonesome girl, receives a small boost in her self-esteem thanks to her protector, Joker.
Rei Kawasumi, the lead vocalist of his high school band Violets, seeks guidance from Haruhiko Tsuchiya due to their lack of popularity. Tsuchiya, known as Khaki P online and a respected composer, suggests to Rei that he should cross-dress and adopt feminine traits to appeal to a wider audience. The chapter ends with Moshi Bare, an unrelated 4-panel comic, and the author's afterword.
After being turned down by a girl he's fond of and getting hit by Rukawa, a rival, for interrupting his confession to the girl, Akagi seeks retribution against Rukawa. Motivated by multiple reasons, Akagi and his teammates propose a basketball match against Rukawa and his team in the regional championship. Which team will emerge victorious?
Having witnessed her father being taken away by a loan shark and subsequently found dead, Da Ra Ji is resolute in seeking revenge.
Japan has been divided into feudal regions and is now under the control of foreign powers in the distant future. Eight vessels assembled to create a floating city known as Musashi loom above. Those who study on Musashi will participate in a battle that will determine the fate of the planet.
Kids, quicken your pace, grow up, seize your arms... This marks our teen years - This signals our dilemma. This is our combat.
The Fashion Club for Crossdressers, consisting of three male students, delves into their concealed passions. A new nurse imparts a lesson in patient care through A Nurse's Passionate Thermometry, while a boy meets a charming girl at a hot spring in Steam Trap. Confession and Before and After Swimsuit follow suit. Furthermore, a professor creates a magical ear pick in Magical Earpick Panic, which induces love in anyone whose ears are cleaned with it. The Striped Panties of Destiny provides a secretive and appetizing solution for a boy's craving (Project H).
This is a brief story about the Demon of Love, an Incubus that must consume the essence of 10,000 women to become a Full Demon. The twist is that the last person the Incubus selects is actually a boy! In order to finish his mission to become a Full Demon, the Incubus opts to reside with the boy. Although it's a comedic tale, it isn't shounen-ai.
The elder sister deceives her younger sibling by convincing him that wearing her outdated bloomers would make him run faster.
The 4koma Anthology, recognized as the official publication by Dengeki Comics EX.
